Depyrogenation Ovens are designed to reach maximum temperatures up to 280° C. It can be self-sufficient relay logic or PLC and integrated with process PLC. A unique mounting system for the HEPA filter reduces particulate concentrations. The system collects data for process validation, monitors operations relative to control limits, and communicates with external data processing equipment. These have stainless steel flashing and bioseal connection to the clean room. These are equipped with monitoring ports for testing fresh air, exhaust & recirculating HEPA filters and interlocked doors with dual contact seals.